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Inhibition of VEGF Expression and Corneal Neovascularization by siRNA Targeting Cytochrome P450 4B1

Injury to the cornea leads to formation of mediators that initiate and amplify inflammatory responses and neovascularization. Among these are lipid mediators generated by a cytochrome P450 (CYP) enzyme identified as CYP4B1. Increased corneal CYP4B1 expression increases limbal angiogenic activity thr...

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Detalhes bibliográficos
Main Authors: Seta, Francesca, Patil, Kiran, Bellner, Lars, Mezentsev, Alexandre, Kemp, Rowena, Dunn, Michael W., Schwartzman, Michal Laniado
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128778/
https://ncbi.nlm.nih.gov/pubmed/17991614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2007.05.001
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