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TGF-β1 Suppresses T Cell Infiltration and VP2 Puff B Mutation Enhances Apoptosis in Acute Polioencephalitis Induced by Theiler’s Virus

GDVII and DA strains of Theiler’s murine encephalomyelitis virus (TMEV) differ in VP2 puff B. One week after GDVII virus infection, SJL/J mice had large numbers of TUNEL(+) apoptotic cells with a relative lack of T cell infiltration in the brain. DA viruses with mutation in puff B induced higher lev...

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Hlavní autoři: Tsunoda, Ikuo, Libbey, Jane E., Fujinami, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128758/
https://ncbi.nlm.nih.gov/pubmed/17804084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.07.026
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