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TGF-β1 Suppresses T Cell Infiltration and VP2 Puff B Mutation Enhances Apoptosis in Acute Polioencephalitis Induced by Theiler’s Virus

GDVII and DA strains of Theiler’s murine encephalomyelitis virus (TMEV) differ in VP2 puff B. One week after GDVII virus infection, SJL/J mice had large numbers of TUNEL(+) apoptotic cells with a relative lack of T cell infiltration in the brain. DA viruses with mutation in puff B induced higher lev...

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Bibliografiske detaljer
Main Authors: Tsunoda, Ikuo, Libbey, Jane E., Fujinami, Robert S.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128758/
https://ncbi.nlm.nih.gov/pubmed/17804084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.07.026
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