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Theiler’s Viruses with Mutations in Loop I of VP1 Lead to Altered Tropism and Pathogenesis

Theiler’s murine encephalomyelitis viruses are picornaviruses that can infect the central nervous system. The DA strain produces an acute polioencephalomyelitis followed by a chronic demyelinating disease in its natural host, the mouse. The ability of DA virus to induce a demyelinating disease rende...

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Detalhes bibliográficos
Main Authors: McCright, Ingeborg J., Tsunoda, Ikuo, Whitby, Frank G., Fujinami, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104039/
https://ncbi.nlm.nih.gov/pubmed/10074129
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