Theiler’s Viruses with Mutations in Loop I of VP1 Lead to Altered Tropism and Pathogenesis

Theiler’s murine encephalomyelitis viruses are picornaviruses that can infect the central nervous system. The DA strain produces an acute polioencephalomyelitis followed by a chronic demyelinating disease in its natural host, the mouse. The ability of DA virus to induce a demyelinating disease rende...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	McCright, Ingeborg J., Tsunoda, Ikuo, Whitby, Frank G., Fujinami, Robert S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104039/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2814-2824.1999
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