Phosphorylation of the PCNA binding domain of the large subunit of replication factor C on Thr(506) by cyclin-dependent kinases regulates binding to PCNA
Replication factor C (RF-C) complex binds to DNA primers and loads PCNA onto DNA, thereby increasing the processivity of DNA polymerases. We have previously identified a distinct region, domain B, in the large subunit of human RF-C (RF-Cp145) which binds to PCNA. We show here that the functional int...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212794/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg692 |
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