Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution

Using a sordarin derivative, an antifungal drug, it was possible to determine the structure of a eukaryotic ribosome⋅EF2 complex at 17.5 Å resolution by three-dimensional (3D) cryo-electron microscopy. EF2 is directly visible in the 3D map and the overall arrangement of the complex from Saccharomyce...

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Autors principals: Gomez-Lorenzo, Maria G., Spahn, Christian M.T., Agrawal, Rajendra K., Grassucci, Robert A., Penczek, Pawel, Chakraburtty, Kalpana, Ballesta, Juan P.G., Lavandera, Jose L., Garcia-Bustos, Jose F., Frank, Joachim
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC212750/
https://ncbi.nlm.nih.gov/pubmed/10835368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2710
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