Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus

We describe a general approach for achieving efficient and cell type-specific expression of exogenous genes in photoreceptor cells of the mammalian retina. Recombinant adeno-associated virus (rAAV) vectors were used to transfer the bacterial lacZ gene or a synthetic green fluorescent protein gene (g...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Flannery, John G., Zolotukhin, Sergei, Vaquero, M. Isabel, LaVail, Matthew M., Muzyczka, Nicholas, Hauswirth, William W.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1997
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6916
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