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Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus

We describe a general approach for achieving efficient and cell type-specific expression of exogenous genes in photoreceptor cells of the mammalian retina. Recombinant adeno-associated virus (rAAV) vectors were used to transfer the bacterial lacZ gene or a synthetic green fluorescent protein gene (g...

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Detalhes bibliográficos
Main Authors: Flannery, John G., Zolotukhin, Sergei, Vaquero, M. Isabel, LaVail, Matthew M., Muzyczka, Nicholas, Hauswirth, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21259/
https://ncbi.nlm.nih.gov/pubmed/9192666
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