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Selective binding of bacterial toxins to major histocompatibility complex class II-expressing cells is controlled by invariant chain and HLA-DM

Bacterial superantigens (SAgs) bind to major histocompatibility complex (MHC) class II molecules and activate T cells in a Vβ-restricted fashion. We recently identified subsets of HLA-DR1 molecules that show selectivity for SAgs. Here, we extend these observations by showing that different cell line...

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Detalhes bibliográficos
Main Authors: Lavoie, Pascal M., Thibodeau, Jacques, Cloutier, Isabelle, Busch, Robert, Sékaly, Rafick-P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21255/
https://ncbi.nlm.nih.gov/pubmed/9192662
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