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Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity

We have developed an immunotherapy in which tumor cells transfected with syngeneic major histocompatibility complex (MHC) class II genes are cell-based vaccines for the treatment of established tumor and metastatic disease. If this strategy is to be used clinically, convenient methods for generating...

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Detalhes bibliográficos
Main Authors: Armstrong, Todd D., Clements, Virginia K., Martin, Brian K., Ting, Jenny P.-Y., Ostrand-Rosenberg, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21254/
https://ncbi.nlm.nih.gov/pubmed/9192661
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