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TR4 Orphan Nuclear Receptor functions as an Apoptosis Modulator via Regulation of Bcl-2 gene Expression
While Bcl-2 plays an important role in cell apoptosis, its relationship to the orphan nuclear receptors remains unclear. Here we report that mouse embryonic fibroblast (MEF) cells prepared from TR4-deficient (TR4(−/−)) mice are more susceptible to UV-irradiation mediated apoptosis compared to TR4-Wi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2121606/ https://ncbi.nlm.nih.gov/pubmed/17655826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.168 |
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