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TR4 nuclear receptor functions as a tumor suppressor for prostate tumorigenesis via modulation of DNA damage/repair system

Testicular nuclear receptor 4 (TR4), a member of the nuclear receptor superfamily, plays important roles in metabolism, fertility and aging. The linkage of TR4 functions in cancer progression, however, remains unclear. Using three different mouse models, we found TR4 could prevent or delay prostate...

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Detalhes bibliográficos
Main Authors: Lin, Shin-Jen, Lee, Soo Ok, Lee, Yi-Fen, Miyamoto, Hiroshi, Yang, Dong-Rong, Li, Gonghui, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043245/
https://ncbi.nlm.nih.gov/pubmed/24583925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu052
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