TR4 Orphan Nuclear Receptor functions as an Apoptosis Modulator via Regulation of Bcl-2 gene Expression

While Bcl-2 plays an important role in cell apoptosis, its relationship to the orphan nuclear receptors remains unclear. Here we report that mouse embryonic fibroblast (MEF) cells prepared from TR4-deficient (TR4(−/−)) mice are more susceptible to UV-irradiation mediated apoptosis compared to TR4-Wi...

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Main Authors: Kim, Eungseok, Ma, Wen-Lung, Lin, Din-Lii, Inui, Shigeki, Chen, Yuh-Ling, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121606/
https://ncbi.nlm.nih.gov/pubmed/17655826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.168
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