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IN VIVO ACTIVITY OF TUMOR NECROSIS FACTOR (TNF) MUTANTS: Secretory but Not Membrane-Bound TNF Mediates the Regression of Retrovirally Transduced Murine Tumor
We have previously demonstrated that murine tumor cells transduced with a retrovirus containing the cDNA encoding wild-type human TNF regress in vivo when injected into immunocompetent mice; this regression is T cell mediated. To determine whether membrane-associated or secreted TNF was responsible...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2121327/ https://ncbi.nlm.nih.gov/pubmed/1517571 |
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