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MURINE TUMOR CELLS TRANSDUCED WITH THE GENE FOR TUMOR NECROSIS FACTOR-α: Evidence for Paracrine Immune Effects of Tumor Necrosis Factor against Tumors

Studies of the anti-tumor activity of TNF-α in vivo have been hampered by the need to administer systemically toxic doses of the cytokine to obtain a curative response. To facilitate studies of the effect of high local concentrations of TNF-α on tumor growth and host immunity, a newly induced murine...

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Detalhes bibliográficos
Main Authors: ASHER, A. L., MULÉ, J . J., KASID, A, RESTIFO, N. P., SALO, J . C., REICHERT, C. M., JAFFE, G., FENDLY, B, KRIEGLER, M., ROSENBERG, S. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950469/
https://ncbi.nlm.nih.gov/pubmed/2016545
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