The c-FLIP–NH(2) terminus (p22-FLIP) induces NF-κB activation

c-FLIP proteins (isoforms: c-FLIP(L), c-FLIP(S), and c-FLIP(R)) play an essential role in the regulation of death receptor–induced apoptosis. Here, we demonstrate that the cytoplasmic NH(2)-terminal procaspase-8 cleavage product of c-FLIP (p22-FLIP) found in nonapoptotic malignant cells, primary T a...

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Bibliographic Details
Main Authors: Golks, Alexander, Brenner, Dirk, Krammer, Peter H., Lavrik, Inna N.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121210/
https://ncbi.nlm.nih.gov/pubmed/16682493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051556
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