Mechanisms imposing the Vβ bias of Vα14 natural killer T cells and consequences for microbial glycolipid recognition

Mouse and human natural killer T (NKT) cells recognize a restricted set of glycosphingolipids presented by CD1d molecules, including self iGb3 and microbial α-glycuronosylceramides. The importance of the canonical Vα14-Jα18 TCR α chain for antigen recognition by NKT cells is well recognized, but the...

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Bibliographic Details
Main Authors: Wei, Datsen G., Curran, Shane A., Savage, Paul B., Teyton, Luc, Bendelac, Albert
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121203/
https://ncbi.nlm.nih.gov/pubmed/16651387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060418
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