Scavenger receptors target glycolipids for natural killer T cell activation

NKT cells are innate-like T cells with powerful regulatory functions that are a promising target for immunotherapy. The efficacy of glycolipids, such as the prototypic NKT cell antagonist α-galactosylceramide (αGalCer), is currently being evaluated in clinical trials, but little is known about facto...

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Hlavní autoři: Freigang, Stefan, Landais, Elise, Zadorozhny, Victoria, Kain, Lisa, Yoshida, Kenji, Liu, Yang, Deng, Shenglou, Palinski, Wulf, Savage, Paul B., Bendelac, Albert, Teyton, Luc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484437/
https://ncbi.nlm.nih.gov/pubmed/23064364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62267
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