Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2
The prohormone convertase SPC2 (PC2) participates in the processing of proinsulin, proglucagon, and a variety of other neuroendocrine precursors, acting either alone or in conjunction with the structurally related dense-core granule convertase SPC3 (PC3/PC1). We have generated a strain of mice lacki...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6646 |
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