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Polyamines are essential for cell transformation by pp60v-src: delineation of molecular events relevant for the transformed phenotype
Ornithine decarboxylase (ODC), the key enzyme of polyamine biosynthesis, becomes upregulated during cell proliferation and transformation. Here we show that intact ODC activity is needed for the acquisition of a transformed phenotype in rat 2R cells infected with a temperature-sensitive mutant of Ro...
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| Natura: | Artigo |
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| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
1993
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2119593/ https://ncbi.nlm.nih.gov/pubmed/7688751 |
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