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Expression of a transgenic T cell receptor beta chain enhances collagen- induced arthritis

SWR/J transgenic (tg) mice were generated expressing the TCR beta chain derived from an anticollagen type II (CII) arthritogenic T cell clone. The SWR/J strain was selected because it is resistant to collagen- induced arthritis (CIA) and lacks the V beta gene segment used by the T cell clone. Expres...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119315/
https://ncbi.nlm.nih.gov/pubmed/1386871
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