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Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes

We have generated for the first time monoclonal antibodies (mAbs) specific for topoisomerase I (topo I) from scleroderma patients, and tight skin mice which develop a scleroderma-like syndrome. The epitope specificity of these antibodies has been determined using a series of fusion proteins containi...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119171/
https://ncbi.nlm.nih.gov/pubmed/1372644
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