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Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

Thalidomide selectively inhibits the production of human monocyte tumor necrosis factor alpha (TNF-alpha) when these cells are triggered with lipopolysaccharide and other agonists in culture. 40% inhibition occurs at the clinically achievable dose of the drug of 1 micrograms/ml. In contrast, the amo...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118820/
https://ncbi.nlm.nih.gov/pubmed/1997652
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