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Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

We have examined at the molecular level the CDR3 and adjacent regions in peripheral blood B lymphocytes of normal individuals. A total of 111 sequences (12-28 sequences from six individuals) were obtained after cloning of the polymerase chain reaction-amplified segments into plasmids or phage. The a...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118795/
https://ncbi.nlm.nih.gov/pubmed/1899102
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