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The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids

Different vectors were constructed that expressed the human interferon- beta (IFN-beta) mRNA constitutively and contained various deletions in the 3' untranslated region (UTR). AU-rich sequences in the 3' UTR were specifically deleted in two vectors. Cell lines secreting human IFN- beta we...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118786/
https://ncbi.nlm.nih.gov/pubmed/1988537
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