The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells

The Wiskott-Aldrich syndrome, a primary human immunodeficiency, results from defective expression of the hematopoietic-specific cytoskeletal regulator Wiskott-Aldrich syndrome protein (WASP). Because CD4(+)CD25(+)Foxp3(+) naturally occurring regulatory T (nTreg) cells control autoimmunity, we asked...

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Autores principales: Maillard, Michel H., Cotta-de-Almeida, Vinicius, Takeshima, Fuminao, Nguyen, Deanna D., Michetti, Pierre, Nagler, Cathryn, Bhan, Atul K., Snapper, Scott B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118715/
https://ncbi.nlm.nih.gov/pubmed/17296786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061338
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