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Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease

CD4(+)Foxp3(+) regulatory T cells (T reg) are essential for maintaining self-tolerance, but their functional mechanisms and sites of action in vivo are poorly defined. We examined the homing receptor expression and tissue distribution of T reg cells in the steady state and determined whether alterin...

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Bibliographische Detailangaben
Hauptverfasser: Sather, Blythe D., Treuting, Piper, Perdue, Nikole, Miazgowicz, Mike, Fontenot, Jason D., Rudensky, Alexander Y., Campbell, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118615/
https://ncbi.nlm.nih.gov/pubmed/17548521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070081
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