Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy

Specific targets of cellular immunity in human premalignancy are largely unknown. Monoclonal gammopathy of undetermined significance (MGUS) represents a precursor lesion to myeloma (MM). We show that antigenic targets of spontaneous immunity in MGUS differ from MM. MGUS patients frequently mount a h...

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Main Authors: Spisek, Radek, Kukreja, Anjli, Chen, Lin-Chi, Matthews, Phillip, Mazumder, Amitabha, Vesole, David, Jagannath, Sundar, Zebroski, Henry A., Simpson, Andrew J.G., Ritter, Gerd, Durie, Brian, Crowley, John, Shaughnessy, John D., Scanlan, Matthew J., Gure, Ali O., Barlogie, Bart, Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118551/
https://ncbi.nlm.nih.gov/pubmed/17389240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062387
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