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Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection
Efficient maintenance of memory CD8 T cells is central to long-term protective immunity. IL-7– and IL-15–driven homeostatic proliferation is essential for long-term memory CD8 T cell persistence after acute infections. During chronic infections, however, virus-specific CD8 T cells respond poorly to...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118542/ https://ncbi.nlm.nih.gov/pubmed/17420267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061937 |
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