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Repression of BCL-6 is required for the formation of human memory B cells in vitro

Memory B cells provide rapid protection to previously encountered antigens; however, how these cells develop from germinal center B cells is not well understood. A previously described in vitro culture system using human tonsillar germinal center B cells was used to study the transcriptional changes...

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Detalhes bibliográficos
Main Authors: Kuo, Tracy C., Shaffer, Arthur L., Haddad, Joseph, Choi, Yong Sung, Staudt, Louis M., Calame, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118536/
https://ncbi.nlm.nih.gov/pubmed/17403935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062104
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