A novel M cell–specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses

Mucosally ingested and inhaled antigens are taken up by membranous or microfold cells (M cells) in the follicle-associated epithelium of Peyer's patches or nasopharynx-associated lymphoid tissue. We established a novel M cell–specific monoclonal antibody (mAb NKM 16–2-4) as a carrier for M cell...

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Detalhes bibliográficos
Main Authors: Nochi, Tomonori, Yuki, Yoshikazu, Matsumura, Akiko, Mejima, Mio, Terahara, Kazutaka, Kim, Dong-Young, Fukuyama, Satoshi, Iwatsuki-Horimoto, Kiyoko, Kawaoka, Yoshihiro, Kohda, Tomoko, Kozaki, Shunji, Igarashi, Osamu, Kiyono, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118513/
https://ncbi.nlm.nih.gov/pubmed/17984304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070607
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