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Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

Mast cells are protective against snake venom sarafotoxins that belong to the endothelin (ET) peptide family. The molecular mechanism underlying this recently recognized innate defense pathway is unknown, but secretory granule proteases have been invoked. To specifically disrupt a single protease fu...

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Detalhes bibliográficos
Main Authors: Schneider, Lars A., Schlenner, Susan M., Feyerabend, Thorsten B., Wunderlin, Markus, Rodewald, Hans-Reimer
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118486/
https://ncbi.nlm.nih.gov/pubmed/17923505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071262
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