Loss of Histochemical Identity in Mast Cells Lacking Carboxypeptidase A

Mast cell carboxypeptidase A (Mc-cpa) is a highly conserved secretory granule protease. The onset of expression in mast cell progenitors and lineage specificity suggest an important role for Mc-cpa in mast cells. To address the function of Mc-cpa, we generated Mc-cpa-null mice. Mc-cpa(−)(/)(−) mast...

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Detalhes bibliográficos
Main Authors: Feyerabend, Thorsten B., Hausser, Heinz, Tietz, Annette, Blum, Carmen, Hellman, Lars, Straus, Anita H., Takahashi, Hélio K., Morgan, Ellen S., Dvorak, Ann M., Fehling, Hans Jörg, Rodewald, Hans-Reimer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168831/
https://ncbi.nlm.nih.gov/pubmed/15988029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.14.6199-6210.2005
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