Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

For decades, in vitro expansion of transplantable hematopoietic stem cells (HSCs) has been an elusive goal. Here, we demonstrate that multipotent adult progenitor cells (MAPCs), isolated from green fluorescent protein (GFP)-transgenic mice and expanded in vitro for >40–80 population doublings, ar...

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Main Authors: Serafini, Marta, Dylla, Scott J., Oki, Masayuki, Heremans, Yves, Tolar, Jakub, Jiang, Yuehua, Buckley, Shannon M., Pelacho, Beatriz, Burns, Terry C., Frommer, Sarah, Rossi, Derrick J., Bryder, David, Panoskaltsis-Mortari, Angela, O'Shaughnessy, Matthew J., Nelson-Holte, Molly, Fine, Gabriel C., Weissman, Irving L., Blazar, Bruce R., Verfaillie, Catherine M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118428/
https://ncbi.nlm.nih.gov/pubmed/17227908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061115
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