Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4(+) T cells after FcγRII-mediated uptake

Plasmacytoid dendritic cells (pDCs) contribute to innate antiviral immune responses by producing type I interferons. Although human pDCs can induce T cell responses upon viral infection, it remains unclear if pDCs can present exogenous antigens. Here, we show that human pDCs exploit FcγRII (CD32) to...

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Hlavní autoři: Benitez-Ribas, Daniel, Adema, Gosse J., Winkels, Gregor, Klasen, Ina S., Punt, Cornelis J.A., Figdor, Carl G., de Vries, I. Jolanda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
Témata:
Brief Definitive Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118356/
https://ncbi.nlm.nih.gov/pubmed/16785312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052364
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