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Interleukin 4 Reduces Expression of Inhibitory Receptors on B Cells and Abolishes CD22 and FcγRII-mediated B Cell Suppression

Inhibitory receptors CD22, FcγRII (CD32), CD72, and paired immunoglobulin-like receptor (PIR)-B are critically involved in negatively regulating the B cell immune response and in preventing autoimmunity. Here we show that interleukin 4 (IL-4) reduces expression of all four on activated B cells at th...

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Detalhes bibliográficos
Main Authors: Rudge, Elizabeth U., Cutler, Antony J., Pritchard, Nicholas R., Smith, Kenneth G.C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193690/
https://ncbi.nlm.nih.gov/pubmed/11956299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011435
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