CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4(+) T reg cells

Regulatory T (T reg) cells are critical regulators of immune tolerance. Most T reg cells are defined based on expression of CD4, CD25, and the transcription factor, FoxP3. However, these markers have proven problematic for uniquely defining this specialized T cell subset in humans. We found that the...

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Autori principali: Liu, Weihong, Putnam, Amy L., Xu-yu, Zhou, Szot, Gregory L., Lee, Michael R., Zhu, Shirley, Gottlieb, Peter A., Kapranov, Philipp, Gingeras, Thomas R., de St. Groth, Barbara Fazekas, Clayberger, Carol, Soper, David M., Ziegler, Steven F., Bluestone, Jeffrey A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118339/
https://ncbi.nlm.nih.gov/pubmed/16818678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060772
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