A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis

It was recently demonstrated that interleukin (IL)-23–driven IL-17–producing (ThIL-17) T cells mediate inflammatory pathology in certain autoimmune diseases. We show that the induction of antigen-specific ThIL-17 cells, but not T helper (Th)1 or Th2 cells, by immunization with antigens and adjuvants...

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Bibliografiske detaljer
Main Authors: Sutton, Caroline, Brereton, Corinna, Keogh, Brian, Mills, Kingston H.G., Lavelle, Ed C.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Brief Definitive Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118338/
https://ncbi.nlm.nih.gov/pubmed/16818675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060285
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