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Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
CD28 plays a critical role in T cell immune responses. Although the kinase Akt has been shown to act downstream of CD28 in T helper (Th)1 cytokine induction, it does not induce Th2 cytokines such as interleukin 4 (IL-4). We recently reported that phosphoinositide-dependent kinase 1 (PDK1) partially...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118337/ https://ncbi.nlm.nih.gov/pubmed/16785309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051715 |
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