Nepmucin, a novel HEV sialomucin, mediates L-selectin–dependent lymphocyte rolling and promotes lymphocyte adhesion under flow

Lymphocyte trafficking to lymph nodes (LNs) is initiated by the interaction between lymphocyte L-selectin and certain sialomucins, collectively termed peripheral node addressin (PNAd), carrying specific carbohydrates expressed by LN high endothelial venules (HEVs). Here, we identified a novel HEV-as...

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Detalhes bibliográficos
Main Authors: Umemoto, Eiji, Tanaka, Toshiyuki, Kanda, Hidenobu, Jin, Soojung, Tohya, Kazuo, Otani, Kazuhiro, Matsutani, Takahiro, Matsumoto, Masanori, Ebisuno, Yukihiko, Jang, Myoung Ho, Fukuda, Minoru, Hirata, Takako, Miyasaka, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118321/
https://ncbi.nlm.nih.gov/pubmed/16754720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052543
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