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T helper type 1–specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-γ promoter are Stat4 dependent

Transcriptional competence of the interferon-γ (IFN-γ) locus is enhanced as Th1 effectors develop from naive CD4 T lymphocytes; conversely, this gene is repressed during Th2 differentiation. We now show that the Switch (Swi)–sucrose nonfermenter (SNF) component Brahma-related gene 1 (Brg1) is recrui...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Fuping, Boothby, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118309/
https://ncbi.nlm.nih.gov/pubmed/16717115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060066
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