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Loss of the proapoptotic protein, Bim, breaks B cell anergy

Although B cells that respond with high avidity to self-antigen are eliminated early in their development, many autoreactive B cells escape elimination and are tolerized later in their lives via anergy. Anergic B cells are unresponsive to antigen and die prematurely. It has been suggested that the p...

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מידע ביבליוגרפי
Main Authors: Oliver, Paula M., Vass, Tibor, Kappler, John, Marrack, Philippa
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118238/
https://ncbi.nlm.nih.gov/pubmed/16520387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051407
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