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In vivo sites and cellular mechanisms of T reg cell–mediated suppression

Regulatory CD4 T (T reg) cells control immune responses to self-antigens and pathogens. However, where T reg cells act to curtail effector T cells in vivo and what stage of effector T cell activation or differentiation is targeted by T reg cells remain unknown. Furthermore, a requirement for direct...

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Bibliographic Details
Main Authors: Rudensky, Alexander Y., Campbell, Daniel J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118229/
https://ncbi.nlm.nih.gov/pubmed/16533888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060214
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