Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

The physiological role of B cell lymphoma 2 (Bcl-2) homology 3–only proteins has been investigated in mice lacking the individual genes identifying rate-limiting roles for Bim (Bcl-2–interacting mediator of cell death) and Puma (p53–up-regulated modulator of apoptosis) in apoptosis induction. The lo...

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Autores principales: Erlacher, Miriam, Labi, Verena, Manzl, Claudia, Böck, Günther, Tzankov, Alexandar, Häcker, Georg, Michalak, Ewa, Strasser, Andreas, Villunger, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118188/
https://ncbi.nlm.nih.gov/pubmed/17178918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061552
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