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Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

To explore the interactions between regulatory T cells and pathogenic effector cytokines, we have developed a model of a T cell–mediated systemic autoimmune disorder resembling graft-versus-host disease. The cytokine responsible for tissue inflammation in this disorder is interleukin (IL)-17, wherea...

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Détails bibliographiques
Auteurs principaux: Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118184/
https://ncbi.nlm.nih.gov/pubmed/17130300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061341
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