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Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes

Breakdown of tolerance leads to autoimmunity due to emergence of autoreactive T or B cell clones. Autoimmune diseases predispose to lymphoid malignancies and lymphoid malignancies, conversely, can manifest as autoimmune diseases. While it has been clear for a long time that a competitive advantage a...

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Autors principals: Knoechel, Birgit, Lohr, Jens G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839094/
https://ncbi.nlm.nih.gov/pubmed/23880067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.06.012
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