A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2

Commensalism is critical to a healthy Th1/Th2 cell balance. Polysaccharide A (PSA), which is produced by the intestinal commensal Bacteroides fragilis, activates CD4(+) T cells, resulting in a Th1 response correcting the Th2 cell skew of germ-free mice. We identify Toll-like receptors as crucial to...

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Main Authors: Wang, Qun, McLoughlin, Rachel M., Cobb, Brian A., Charrel-Dennis, Marie, Zaleski, Kathleen J., Golenbock, Douglas, Tzianabos, Arthur O., Kasper, Dennis L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118167/
https://ncbi.nlm.nih.gov/pubmed/17178920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062008
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