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Reversal of airway hyperresponsiveness by induction of airway mucosal CD4(+)CD25(+) regulatory T cells

An important feature of atopic asthma is the T cell–driven late phase reaction involving transient bronchoconstriction followed by development of airways hyperresponsiveness (AHR). Using a unique rat asthma model we recently showed that the onset and duration of the aeroallergen-induced airway mucos...

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Autori principali: Strickland, Deborah H., Stumbles, Philip A., Zosky, Graeme R., Subrata, Lily S., Thomas, Jenny A., Turner, Debra J., Sly, Peter D., Holt, Patrick G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118157/
https://ncbi.nlm.nih.gov/pubmed/17088431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060155
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