Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice

BACKGROUND: To characterise the acute physiological and inflammatory changes induced by low-dose RSV infection in mice. METHODS: BALB/c mice were infected as adults (8 wk) or weanlings (3 wk) with 1 × 10(5 )pfu of RSV A2 or vehicle (intranasal, 30 μl). Inflammation, cytokines and inflammatory marker...

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Autores principales: Collins, Rachel A, Gualano, Rosa C, Zosky, Graeme R, Atkins, Constance L, Turner, Debra J, Colasurdo, Giuseppe N, Sly, Peter D
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325022/
https://ncbi.nlm.nih.gov/pubmed/16324223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-142
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