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Plasma cell S1P(1) expression determines secondary lymphoid organ retention versus bone marrow tropism

After induction in secondary lymphoid organs, a subset of antibody-secreting cells (ASCs) homes to the bone marrow (BM) and contributes to long-term antibody production. The factors determining secondary lymphoid organ residence versus BM tropism have been unclear. Here we demonstrate that in mice t...

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Detalhes bibliográficos
Main Authors: Kabashima, Kenji, Haynes, Nicole M., Xu, Ying, Nutt, Stephen L., Allende, Maria L., Proia, Richard L., Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118149/
https://ncbi.nlm.nih.gov/pubmed/17101733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061289
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